Our research project
Melomanes aims to train a new generation of highly skilled doctoral researchers to emerge with a high-level training in the multidisciplinary field of nanomedicine. The goal is to develop a therapy for metastatic melanoma combining magnetic nanoparticles and CAR-T cells.
The strategy is to use the nanoparticles to induce damage on the tumor microenvironment, by magnetic and optic hyperthermia, in order to facilitate the infiltration of CAR-T cells. This therapeutic approach combining hyperthermia and immunotherapy is versatile, as it could be also applied to other types of solid tumors.