Improving metastatic melanoma treatments
Metastatic melanoma is a hard-to-treat disease and it remains as one of the most worrisome cancer. There is an urgent need to improve the current therapies that have a limited efficacy.
Melomanes is a training-by-research project on an innovative immunotherapy treatment enhanced by nanoparticles.
Our research project
Melomanes aims to train a new generation of highly skilled doctoral researchers to emerge with a high-level training in the multidisciplinary field of nanomedicine.
Our goal? Develop a therapy for metastatic melanoma combining magnetic nanoparticles and CAR-T cells.
Our strategy? Use nanoparticles to induce damage on the tumor microenvironment, by magnetic and optic hyperthermia, in order to facilitate the infiltration of CAR-T cells.
Our approach? Integrate the safety, sustainability and ethics aspects within the research on the nanoparticles and immunotherapy.
Our impact beyond metastatic melanoma? Our therapeutic approach, combining hyperthermia and immunotherapy, is versatile. It could be applied to other types of solid tumors.
